Update: Visium for FFPE

Recently, 10x Genomics has launched their Visium for FFPE kit. At Single Cell Discoveries, we have decided to include this in our Visium Pilot Program. What is Visium? Visium Spatial Gene Expression allows you to analyze the whole transcriptome of your tissue section. Previously, this was only available for fresh frozen tissue sections. Now, it…

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Becoming a 10x Genomics Certified Service Provider

We are proud to announce that as of March 29, 2021, we are a 10x Genomics Certified Service Provider. We have been certified for the Single Cell Gene Expression and Single Cell Immune Profiling solutions.  What does it mean?  The certification that we received from 10x Genomics means that we perform both methods according to the standards set by 10x Genomics. Therefore,…

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Quotation

After discussing your project set up with our specialist, you can request a quotation on our website or by sending an email to sales@scdiscoveries.com. Required information The information we need to make a quotation depends on various parameters of the service you aim for: Bulk RNA seq The number of samples The sequencing depth: STANDARD…

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Revealing an unexpected homogeneity in neuroblastoma

Tumors are usually very heterogeneous and consist of various cancer cell subtypes. Single-cell sequencing can be applied to understand this heterogeneity and often leads to identifying cancer cell subtypes. In this study, there is a surprising outcome: a homogeneous phenotype.   In this scientific collaboration between many institutes in the Netherlands and the UK, researchers were…

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Four reasons to collaborate with a single-cell sequencing service provider

Getting started with single-cell sequencing can be overwhelming.  Most academic institutes have single-cell facilities, but if yours doesn’t or you’re looking for other single-cell techniques, you might want to consider working with a service provider.  Here, we explain why you should consider collaborating with a service provider for single-cell sequencing. 

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Single-cell sequencing: core facility or service provider?

When starting with single-cell sequencing, your might ask yourself: do I make use of a core facility or service provider? There are actually three options for single-cell sequencing. You can either make use of the core facility in your institute, outsource your project to a service provider or do everything by yourself. Here, we explain these…

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How to decide your single-cell sequencing parameters

A single-cell sequencing project has different parameters: the number of samples, cells per sample and reads per cell. But how do you decide how many cells you need? Or how deep you need to sequence? Here, we explain what your choice should be based upon. 

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How can I improve my research with single-cell sequencing?

As we explained before in our blog, “what is single-cell sequencing”, single-cell sequencing allows you to obtain high-resolution data of your sample(s). But how can you use single-cell sequencing to improve your research? Single-cell sequencing improves your understanding of complex biological systems Complex biological systems, such as tumors, organs, the central nervous system, and the immune system, are composed of many different cell (sub-)types. Single-cell sequencing allows…

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