How we tackle cell type annotation
One of the main challenges in single-cell data interpretation is annotating cell types. In this blog, we explain our process of collaborating with clients to analyze single-cell data and assign cell type identity labels.
How we identify a cell
Cell type identification is currently one of the leading applications of single-cell RNA sequencing experiments. How do we do it? In this blog, we zoom in on the nine-step process that takes you from raw sequencing data to assigning cell type labels.
Is 10x Genomics suitable for my project?
10x Genomics solutions may or may not be suitable for your project, depending on your sample type and your number of cells. How do you know?
Organs-on-a-chip, RNA sequencing and drug development
Unlocking the secret to effective cancer treatment? The answer could lie in organ-on-a-chip technology. Researchers of MIMETAS are using organs-on-a-chips to mimic the complex conditions of pancreatic ductal adenocarcinoma. A recent study showed the impact of hypoxia on drugs’ effectiveness, offering potential targets for new drugs. Researchers often report that a lack of suitable experimental…
How to start with 10x Genomics
In the world of single-cell RNA sequencing, 10x Genomics has made a name for itself as a leading provider of high-throughput solutions. But for those new to the field, the prospect of starting with 10x Genomics solutions can be intimidating. That’s why, in this blog post, we’ll show you how to take the first step….
What is a UMAP plot?
Single-cell papers usually show their data in the shape of the UMAP plot. What is it?
Introducing our new pricing
Every year in January, we update our pricing. In this blog, we briefly explain this year’s pricing increase and what this means for you. Adapting prices to inflation As you are probably aware, inflation increased significantly last year in most countries and is anticipated to remain high in 2023. This does not leave our sector…
What does a t-SNE plot show?
You can find a t-SNE plot in almost every single-cell paper. What are the dots, colors, and axes? Learn how to interpret the plot.
CITE-seq: single-cell RNA sequencing plus surface protein analysis
CITE-seq is a method to simultaneously perform single-cell RNA sequencing and single-cell surface protein analysis. But how does this work? And what does it accomplish?
Neuron heterogeneity in the developing mouse brain
Deeply hidden in the brain, the tiny habenula is increasingly associated with different psychological roles. High-scale cellular heterogeneity may explain that multifunctionality. Here, we describe how single-cell RNA sequencing helps describe habenula diversity and function. The habenula is a tiny structure in the brain that is believed to be involved in the regulation of mood…
What is t-SNE?
One of the most recognizable figures in a single-cell paper explained simply. What is it? What is its purpose? And how does t-SNE work?
Insights into the hypertrophic heart with single-cell RNA sequencing
Heritable gene defects can cause the heart muscles to thicken and bring on hypertrophic cardiomyopathy. How this occurs is not entirely clear. This blog describes how single-cell RNA sequencing helps understand the hypertrophic heart and provide directions for future genetic research. Hypertrophic cardiomyopathy is a heritable condition in which the heart thickens. It occurs in…