What is t-SNE?

One of the most recognizable figures in a single-cell paper explained simply. What is it? What is its purpose? And how does t-SNE work?

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Insights into the hypertrophic heart with single-cell RNA sequencing

Heritable gene defects can cause the heart muscles to thicken and bring on hypertrophic cardiomyopathy. How this occurs is not entirely clear. This blog describes how single-cell RNA sequencing helps understand the hypertrophic heart and provide directions for future genetic research. Hypertrophic cardiomyopathy is a heritable condition in which the heart thickens. It occurs in…

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Guiding SARS-CoV-2 vaccine development with single-cell RNA sequencing

The road to an improved coronavirus vaccine is complex. Yet, it is one of the most pressing challenges in the effort to protect against COVID-19. This blog describes how single-cell RNA sequencing helps map out the small steps toward vaccine improvement. The ongoing COVID-19 pandemic is far from an end. Vaccines are at the basis…

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