Neuron heterogeneity in the developing mouse brain
Deeply hidden in the brain, the tiny habenula is increasingly associated with different psychological roles. High-scale cellular heterogeneity may explain that multifunctionality. Here, we describe how single-cell RNA sequencing helps describe habenula diversity and function. The habenula is a tiny structure in the brain that is believed to be involved in the regulation of mood…
Three reasons to start small with single-cell sequencing
When you first start with single-cell sequencing, it’s often best to start small with a pilot project. Here, we explain why. We updated this blog from March 2021 on 5 December 2022. We rewrote it and included a company comparison as a reason to start with a pilot project. Technical and biological validation If you start a…
What is t-SNE?
One of the most recognizable figures in a single-cell paper explained simply. What is it? What is its purpose? And how does t-SNE work?
Insights into the hypertrophic heart with single-cell RNA sequencing
Heritable gene defects can cause the heart muscles to thicken and bring on hypertrophic cardiomyopathy. How this occurs is not entirely clear. This blog describes how single-cell RNA sequencing helps understand the hypertrophic heart and provide directions for future genetic research. Hypertrophic cardiomyopathy is a heritable condition in which the heart thickens. It occurs in…
Marina, welcome to the team!
We are happy to announce that Marina has joined the sales team as a business development representative! Marina will mainly be responsible for the sales pipeline and executing consultation calls with leads and clients. She strives to understand each customer’s specific needs and addresses them with the help of our services. Marina has a background…
New VASA-seq protocol will be launched in June
We will launch VASA-seq 1.1 in June 2023. Read here when you can order and submit current and new VASA-seq cell capture plates.
Niels, welcome to the team!
We joyfully announce that Niels Tjoonk has joined the team as a scientific content marketer! At Single Cell Discoveries, Niels will be responsible for showcasing our work in blog posts, ebooks, whitepapers, videos, and social media content. He obtained his BSc in biomedical sciences at Utrecht Utrecht. Later, that’s also where he got his MSc…
Fredrik, welcome to the team!
We are happy to announce that Fredrik Salmén has joined the team as a data scientist/R&D consultant! At Single Cell Discoveries, Fredrik will be responsible for setting up new methods and improving existing methods offered by Single Cell Discoveries. Fredrik is originally from Stockholm, Sweden. This is also the place where he obtained his MSc…
Florin, welcome to the team!
Florin has joined the data team as a Data Intern. He will be working on the SCD pipelines, helping develop them while analyzing the results and evaluating the performance of the pipelines. Florin is originally from Romania but lived most of his life in Montreal, Canada. He did a bachelor’s in Physics with a minor…
Guiding SARS-CoV-2 vaccine development with single-cell RNA sequencing
The road to an improved coronavirus vaccine is complex. Yet, it is one of the most pressing challenges in the effort to protect against COVID-19. This blog describes how single-cell RNA sequencing helps map out the small steps toward vaccine improvement. The ongoing COVID-19 pandemic is far from an end. Vaccines are at the basis…
Natasa, welcome to the team!
Nataša Josipović has joined the team as a senior lab technician. She is responsible for all 10x Genomics-related experiments and sample processing. Nataša originally comes from Belgrade, Serbia, where she did her BSc studies in Molecular Biology and an MSc in Neurobiology. During her master’s, she studied the role of CD73 in the progression of…
Pablo, welcome to the team!
Pablo will join the Data team as a Junior Bioinformatician. Pablo has a BSc in Biotechnology and an MSc in Computational Biology from the Technical University of Madrid. He did a bachelor’s internship at the University College Cork in Ireland, where he studied early alterations occurring to Tau protein in Alzheimer’s disease. In this study,…