Drug Discovery for Precancerous Liver Disease

Université de Strasbourg and INSERM | Single Cell Discoveries supports scientists all over the world in drug development by helping them investigate the therapeutic mechanism of action at the single-cell level. Here’s the story of how SORT-seq helped advance a novel drug candidate for liver cancer into clinical trials.

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Single-Cell Atlas of the Human Cornea

MERLN Institute for Technology-Inspired Regenerative Medicine | The single-cell cornea atlas published in Scientific Reports was a successful collaboration between Single Cell Discoveries and the Cell Therapy group at MERLN Institute for Technology-Inspired Regenerative Medicine. Here’s the story of that collaboration.

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Colorectal Zebrafish Xenograft Model

Champalimaud Foundation | This research, conducted at the Champalimaud Foundation in Lisbon, is focused on the immune response after implantation of human cancer cells in zebrafish. The cells in the implanted tumors were characterized using SORT-seq. Here, we explain how SORT-seq contributed to this remarkable study. Cancer immunoediting is a process in which the immune…

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Snake Venom Gland Organoids

Hubrecht Institute | Three PhD students, under the supervision of Prof. Dr Hans Clevers in molecular genetics and snake expert Prof. Dr Freek Vonk, conducted this remarkable research in which they developed snake venom-producing organoids. The organoids were characterized using SORT-seq. Here, we explain how the project was done. Snake bites are still a massive…

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