Our COVID-19 research

Use single-cell sequencing for your battle against COVID-19.

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Some of our customers
Genmab
Hubrecht Institute
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This is the logo of the university of Oxford
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Our COVID-19 projects

SARS-CoV-2 in intestinal organoids

A collaborative study in which Dutch research groups show that the SARS-CoV-2 virus is able to infect gut organoids. This research was done at the Hubrecht Institute in Utrecht, the Erasmus MC in Rotterdam, and Maastricht University. The results were published in Science.

At Single Cell Discoveries, we are proud to have been able to assist the researchers with our bulk RNA sequencing services.

 

Virus
Scientists working in the lab with pcr machines

Clear COVID-19

Clear COVID-19 is focused to develop epithelial models from nasal brushing obtained from SARS-CoV-2 patients. Within these models, viral infections may be simulated to select candidate drugs. The consortium partners are Utrecht University Medical Center, Utrecht University, First Health Pharmaceuticals, Vossensteyn Biomedical, QVQ Holding B.V., and Single Cell Discoveries.

We are proud to contribute with our single-cell sequencing expertise.

The project, which started in June 2020, will take approximately 24 months to complete.

Why work with us

  • Dedicated service provider
    With our focus on single-cell sequencing only, we are the one-stop-shop for all your single-cell sequencing projects.
  • Continued support
    We make sure to provide continuous support, even after we have sent you the results from your experiment.
  • Cost-effective services
    We work with you and your budget to make sure you don't have to break the bank.
  • Expert team
    We have been running single-cell experiments since 2012, and have published in numerous high-impact journals
  • Short turnaround times
    From receipt of the samples, you can expect results in 4 - 6 weeks.
  • Based in Europe
    Your samples are processed and sequenced in the European Union (Netherlands & UK)

Our single cell
sequencing services

Because we offer multiple single-cell sequencing platforms, there is always a solution that suits your needs.

10x genomics

High-throughput single-cell sequencing.

Available 10x Genomics services are 3’ Single Cell Gene Expression and 5’ Single Cell Immune Profiling.

  • Analyze thousands of cells per sample
    The 10x Genomics platform allows you to target up to 10,000 cells per sample, resulting in a low cost per cell for high-throughput projects.
  • Combine immune profiling with single-cell transcriptomics
    Analyze the transcriptome, the T-cell and/or B-cell receptor repertoire, cell surface proteins, and antigen-specificity, all at single-cell level with the Single Cell Immune Profiling service.
  • You are not alone
    Currently, the 10x Genomics single-cell platform has been used in more than 1,000 peer-reviewed publications, so you are far from alone in using this technique. Whatever your biological question, chances are that 10x Genomics services will have been used on similar tissue or species.

 

 

10x_genomics
SORT-seq

SORT-seq

Highly cost-effective, plate-based single-cell sequencing. FACS sort your single cells into the wells of our 384-well cell capture plates and send them back to us for further processing.

  • Cost-effective single-cell sequencing
    With prices starting at just over €1000 per sample, SORT-seq is one of the most cost-effective single-cell sequencing methods available.
  • Modular and flexible due to the use of plates
    Working with plates allows you to start small and upscale later. We can start by processing and sequencing one plate per condition. Once the data from the first plate looks good, we can go on to process the rest of the plates. This provides you with tremendous flexibility in scaling up your experiments.
  • Compatible with all sample types
    SORT-seq works even with rare or low quantities of cells. As long as you can fill at least part of a plate with FACS sorting, you can generate single-cell sequencing libraries. Also, SORT-seq can handle cells of all sizes. Cells that are too big for the 10x Genomics system (e.g. cardiomyocytes) can be analyzed with SORT-seq without any issues.

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JULIA_STRENGERS

Julia Strengers

Account Manager

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