An Endogenous Retrovirus Vaccine Encoding an Envelope with a Mutated Immunosuppressive Domain in Combination with Anti-PD1 Treatment Eradicates Established Tumours in Mice
Targeting the endogenous retrovirus protein ‘Envelope’ may protect against cancer. Here, the authors document their development of a virus-like vaccine technology and employ SORT-seq to study the vaccine’s immunogenicity effect on dendritic cells.
- DOI: 10.3390/v15040926
- Services: SORT-seq
- Species: Mouse
- Sample type: Bone marrow, Immune system