p57Kip2 imposes the reserve stem cell state of gastric chief cells
Gastric chief cells are referred to as ‘reserve’ stem cells because they become proliferative and take part in regeneration after injury. The authors employed SORT-seq and doxycycline-based lineage tracing to reveal that p57Kip2 is a molecular switch for the reserve stem cell state of chief cells in mice.
- DOI: 10.1016/j.stem.2022.04.001
- PMID: 35523142
- Services: SORT-seq
- Species: Mouse
- Sample type: Stem cells, Stomach