Transcriptome-module phenotype association study implicates extracellular vesicles biogenesis in Plasmodium falciparum artemisinin resistance.
Artemisin-based combination therapies are a great cure for malaria, but concerns for artemisin resistance in the causative parasite P. falciparum are imminent. Here, the authors study extracellular vesicle formation in the parasite as an artemisin resistance gene expression phenotype with bulk RNA-seq.
- DOI: 10.3389/fcimb.2022.886728
- PMID: 36061874
- Services: Bulk RNA sequencing
- Species: P. falciparum
- Sample type: Parasites