Epicutaneous allergen immunotherapy induces a profound and selective modulation in skin dendritic cell subsets
A fast-expanding method in food allergy health is the epicutaneous allergen immunotherapy or patch test (“plakproef”). Laoubi et al. used SORT-seq, among other methods, to study the contribution of skin dendritic cells to T cell remodeling during patch tests. Their results emphasize that the cornerstone of food allergy desensitization is skin dendritic cells acquiring distinct specializations during the patch test.
- DOI: 10.1016/j.jaci.2022.05.025
- PMID: 35779666