Linking the genotypes and phenotypes of cancer cells in heterogenous populations via real-time optical tagging and image analysis
This paper describes how cells can be optically tagged in real-time based on specific functional cell dynamics, such as fast migration or morphological variation. Moreover, it documents how you can combine optical tagging with single-cell RNA sequencing to link the genotypes and phenotypes of heterogenous tumor populations.
- DOI: 10.1038/s41551-022-00853-x
- PMID: 35301448
- Services: SORT-seq
- Species: Human
- Sample type: Breast, Head and neck mucosa, Tumor tissue