The EMBO Journal January, 2021
by Mart M. Lamers et al.
An organoid-derived bronchioalveolar model for SARS-CoV-2 infection of human alveolar type II-like cells
- DOI: 10.15252/embj.2020105912
- PMID: 33283287
- Services: 10x Genomics, Bulk RNA sequencing, Data analysis
- Species: Human
- Sample type: Lung, Organoids
eLife September, 2020
by Feline W. Lindhout et al.
Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons
- DOI: https://doi.org/10.7554/eLife.58124
- PMID: 32940601
- Services: Bulk RNA sequencing, SORT-seq
- Species: Human
- Sample type: Brain, Stem cells
Science July, 2020
by Mart M. Lamers et al.
SARS-CoV-2 productively infects human gut enterocytes
How can you explain gastrointestinal symptoms after SARS-CoV-2 infection? Lamers et al. demonstrated SARS-CoV-2 replicates in the enterocytes of human intestinal organoids. Bulk mRNA sequencing showed RNA expression changes in infected organoids.
- DOI: 10.1126/science.abc1669
- PMID: 32358202
- Services: Bulk RNA sequencing
- Species: Human
- Sample type: Intestine, Lung
Cell June, 2020
by Joep Beumer et al.
High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells
Beumer et al. describe an organoid-based platform for functional studies of human enteroendocrine cells, the intestines’ hormone-excreting cells. They made a single-cell mRNA atlas for different subtypes and identified the secreted products.
- DOI: 10.1016/j.cell.2020.04.036
- PMID: 32407674
- Services: Bulk RNA sequencing, SORT-seq
- Species: Human
- Sample type: Intestine