Molecular characterization of Barrett’s esophagus at single-cell resolution
Barrett’s esophagus is the premalignant condition of esophageal adenocarcinoma. It is categorized into different stages which correlate with the risk of developing carcinoma. Busslinger et al. performed single-cell RNA sequencing to identify seven genes that facilitate the distinction between different Barrett’s esophagus stages on histological sections.
- DOI: 10.1073/pnas.2113061118
- PMID: 34795059
- Services: SORT-seq
- Species: Human
- Sample type: Esophagus, Tumor tissue