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Our services
We currently offer single-cell, spatial and bulk transcriptomics.
Our R&D team is actively testing new single-cell multi-omic technologies and spatial
modalities to offer additional insight into our clients' biological questions.
Single-cell sequencing
SORT-Seq
Single-cell transcriptomics method utilizing 384-well plates, ideal for low cell counts, FACS sorted populations, and pilot projects. Developed by our founder, exclusively offered by us.
VASA-Seq
Single-cell RNA sequencing method for full- length and total RNA, ideal for analyzing non- coding RNA and complete transcriptomes. Developed by one of our team members, exclusively offered by us.
Spatial transciptomics
Pooled cells
Bulk RNA Sequencing
Comprehensive transcriptome analysis of pooled cell populations, ideal for limited starting material and large projects requiring cell population data.
How we supercharge
your research
Project Design
- Strategize with our PhD-level account executives to decide between multiple single-cell technologies, including two exclusively offered by us.
- Leverage our experience with 200+ clients over 1000+ unique projects.
Sample Processing
- Strategize with our PhD-level account executives to decide between multiple single-cell technologies, including two exclusively offered by us.
- Leverage our experience with 200+ clients over 1000+ unique projects.
Data Analysis
- Strategize with our PhD-level account executives to decide between multiple single-cell technologies, including two exclusively offered by us.
- Leverage our experience with 200+ clients over 1000+ unique projects.
Applications
Cell Type Identification
Identify novel or rare cell types by analyzing gene expression profiles of individual cells and grouping them based on similarities in their transcriptional signatures.
Drug Discovery
By identifying differentially expressed genes in specific cell types, disease states, and responders/non-responders, single cell sequencing can accelerate target and biomarker discovery.
Immune Profiling
High-resolution immune profiling provides insight into functional states of immune cells in response to antigenic stimulation and treatment; BCR and TCR repetoire sequencing can provide starting points for immuno-oncology therapeutic development of monoclonal antibodies or cell therapies.
Research areas
Oncology
Revolutionize cancer research and discover new treatments by measuring the heterogeneity of the tumor microenvironment and probing the molecular mechanisms underlying cancer development and disease progression.
Immunology
Unlock new insights into the mechanisms underlying immune system function, response to stimuli, and involvement in immuno-oncology treatments.
Developmental Biology
Unravel developmental processes to discover molecular mechanisms behind development, genetic diseases, and regeneration.
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Get the Ultimate Guide
Our ultimate guide is a crash-course in single-cell sequencing and will get you up to speed with how it was developed and how you can use it to level up your research.
Why choose SCD?
We are single-cell sequencing experts
We are 100% focused on single-cell and spatial transcriptomics, enabling us to take on both large-scale projects and create customized solutions for each client project.
Our experience is unmatched in the field
We have been working in the single-cell field since 2012. Our co-founder and CEO Mauro Muraro published our SORT- seq technology, and our R&D consultant is the mind behind VASA-seq. We have experience in over 40 organisms and 30 tissues and are able to quickly adapt workflows for novel samples.
We help you stay ahead of the curve
We are committed to continuously integrating leading-edge technologies into our service offerings to ensure clients have access to the latest advancements. Our R&D department works to both internalize the best commercial platforms and advance our own single-cell innovations.
We work with you as a collaborative partner
We are dedicated to maintaining a high- touch, collaborative relationship with clients as we scale our capacity to accommodate larger projects. We act as a thought partner and a catalyst for biological discovery.
"The service of Single Cell Discoveries guarantees a smooth process between customer and company. In case of problems or questions, the scientists reacted competently and immediately, so that answers could be found quickly and flexibly.."
"The service of Single Cell Discoveries guarantees a smooth process between customer and company. In case of problems or questions, the scientists reacted competently and immediately, so that answers could be found quickly and flexibly.."
"Fantastic job made by a really professional and friendly team. I strongly recommend Single Cell Discoveries for sequencing services."
"The service of Single Cell Discoveries guarantees a smooth process between customer and company. In case of problems or questions, the scientists reacted competently and immediately, so that answers could be found quickly and flexibly.."
"Fantastic job made by a really professional and friendly team. I strongly recommend Single Cell Discoveries for sequencing services."
"Donec id lacus ipsum. Integer facilisis nunc quis tellus fermentum malesuada. Nam tristique id ipsum vitae lobortis. Interdum et malesuada fames ac ante ipsum primis in faucibus."
Interested? Connect with
our scientists to get started
Step 1
Consultation
Every project starts with one or more free consultations because no two single-cell projects are the same. Our experienced PhD-level team discusses your biological question, sample type, planning, data analysis options, and other wishes. This will ensure you select the best method for your project and can hit the ground running.
Step 2
Sample Preparation
SORT-seq is a plate-based method. There are two options here. Either you order your SORT-seq plates with us, sort your samples into the plates, and ship them back to us. Or send us your samples and we'll do the sorting for you.
Deliverables
As with all of our services, we provide ongoing support from our single-cell sequencing specialists. For each SORT-seq project, we provide the following:
- Regular updates during processing, including QC reports.
- Raw sequencing data (FASTQ files)
- Raw and filtered gene count tables
- An interactive preliminary analysis report including QC, clustering and differential gene expression analysis
- A Seurat object to do your own analysis with the Seurat pipeline
- A brief explanation from our data team about the quality of your data
FAQ
We advise two plates for each sample or condition. This ensures a technical backup plate is always available in case something goes wrong with shipment or processing.
Content
Content
Our R&D experts
Dylan Mooijman, PhD
HEAD OF R&D
The master chef in our R&D kitchen, Dylan Mooijman oversees improvements to current services and innovation on new methods. He is motivated by pioneering single-cell sequencing technology. Before taking the helm of our R&D unit, Dylan earned a HFSP fellowship to work at EMBL Heidelberg (Ephrussi lab) and a PhD degree at the Van Oudenaarden lab.
Darina Šikrová, PhD
R&D SCIENTIST
Darina Šikrová is focused on optimizing our technologies. She is motivated by solving "impossible problems" and her capabilities earned her a PhD on rare genetic causes and gene therapy for muscular dystrophy disease FSHD.
Buying guide
Which technology is suitable for my project?
Use the buying guide to receive instant advice on what technology is a good candidate for your project.
How can we help?
Want to supercharge your project with single-cell insights?
Connect with our PhD-level scientists to discuss your biological question, timeline, sample types, and other customizations for your single-cell analysis.
