Jeroen, welcome to the team!
Happy to announce that Jeroen Geerligs is a new addition to the lab team as a technician! Jeroen will mainly be responsible for sample processing, sample shipments, and lab maintenance. He will particularly focus on our Bulk RNA services. Jeroen has a background in Molecular Life Sciences at Utrecht University (BSc) and got acquainted with…
Reinke, welcome to the team!
We are happy to announce that Reinke has joined the team as a financial assistant. Reinke’s education actually started in science. She finished the HLO in Utrecht a long time ago. During that time, she worked in a lab and contributed to a paper. Due to circumstances, she was introduced to the world of Finance,…
Sofia, welcome to the team!
Sofia will be working together with R&D and Data teams to analyse data coming from the in-house projects. She obtained her bachelor’s in biology at Stockholm University. For her degree project, Sofia studied yeast with impaired Ca2+ homeostasis and the effect of ubiquinone (CoQ) biosynthesis on their survival. She also did one semester of exchange…
Jenine, welcome to the team!
We are happy to announce that Jenine Kruger has joined the team as a Management Executive! At Single Cell Discoveries, she will be responsible for assisting our CEO, COO, and the heads of the departments: Mauro Muraro, Judith Vivié, Bastiaan Bijl, Lotte Koopman, Andrei Prodan, and Dylan Mooijman. She is originally from South Africa where…
Darina, welcome to the team!
We are happy to announce that Darina has joined the team as a Scientist in R&D department, where she will work on improving the currently offered methods as well as broadening our portfolio by developing new ones. She is originally from Slovakia, where she also obtained her BSc at Comenius University in Bratislava after which…
Manon, welcome to the team!
We are happy to announce that Manon Messchendorp has joined the team as a lab technician! At Single Cell Discoveries, Manon will be responsible for sample processing, sample shipments, and lab maintenance. She obtained her BSc and MSc in Biology at the University of Leiden. During her Bachelor’s internship, she tested the anti-inflammatory and antioxidative…
Identification of cell clusters in the human cornea using single-cell RNA sequencing
In this blog, we describe how single-cell RNA sequencing is used to understand the cellular complexity of the cornea tissue. This blog is based on a study published in Nature in November 2021. The cornea is the part of the eye that allows light to enter and causes refraction of the light. It is composed…
Prediction of future relapse in MLL-rearranged infant ALL by single-cell RNA sequencing
In this blog, we describe how single-cell RNA sequencing allowed to predict which MLL- rearranged infant acute lymphoblastic leukemia (MLL-r iALL) patients are at risk of relapse. Furthermore, it allowed for characterization of the nature of relapse-predicting cells. Acute lymphoblastic leukemia (ALL) in infants is often driven by a specific mutation, in which a part…
A human liver model leads to therapeutic discovery for liver disease
In this blog, we will discuss how single-cell RNA sequencing contributed to the discovery of a therapeutic for the treatment of advanced liver disease. Liver fibrosis can lead to cirrhosis, which is a late-stage liver disease in which a large part of the liver tissue is replaced by fibrotic tissue, and to hepatocellular carcinoma (HCC)….
Kelly, welcome to the team!
We are happy to announce that Kelly Klaassen has joined the team as a Marketing Intern. During her internship for Single Cell Discoveries, she will be responsible for investigating the needs and wants of commercial clients, which can be used for improving Single Cell Discoveries’ offerings. Kelly completed her BSc degree in Biology and Medical…
Transcriptome of human FDCs reveals role in antigen presentation to B cells and regulation of T cells
In this blog, we will discuss the contribution of single-cell RNA sequencing to uncovering the function of human follicular dendritic cells (FDCs) in the germinal center (GC) microenvironment. The GC is a structure in secondary lymphoid tissues, such as tonsils, in which long-lived antibody-secreting plasma cells and memory B cells are produced. Within the GC,…
Andrei, welcome to the team!
We are happy to announce that Andrei Prodan has joined SCD as our new Head of Data Science, where he will coordinate the SCD Data Science team, update and maintain the computational infrastructure and bioinformatics pipelines and manage research collaborations and projects. Andrei is originally from Deva, a small town in Transylvania, Romania. After earning…