Single cell sequencing technologies
single cell sequencing
With different single-cell sequencing platforms available, there is always a solution that suits your needs. Learn about the single-cell sequencing technologies we offer and how they can accelerate your research.
Obtain a single-cell resolution
Single-cell sequencing is a powerful technology enabling researchers to examine individual cells rather than groups of cells. It gives researchers the resolution to obtain genomic, transcriptomic, epigenetic, or proteomic information at a single-cell level.
Map transcriptomic differences between cells
With single-cell transcriptomics, also known as single-cell RNA sequencing, the focus is on identifying single-cell gene expression differences to study cell types and states in a context-specific manner, thereby revealing among other things tissue- specific cellular heterogeneity, novel therpateutic biomarkers and targets, and characterize complex cellular responses to treatment and intervention.
Recognize cellular heterogeneity
Current single-cell sequencing research continues to demonstrate that no two cells are exactly the same. The appreciation of cellular heterogeneity is improving our understanding of complex diseases and empowering the development of new drugs.
Benefit directly from our expertise
Just as with cells, no two research questions are exactly the same. Different research goals, project scopes, tissue types, and cell numbers require different approaches and technologies. This calls for selecting from a diverse single-cell toolkit. Our services overview and buying guide are tools to aid your selection, and our experts are the best resource to leverage in making your decision. Schedule a call today to access their unparalleled experience in single-cell technologies.
We offer multiple single-cell sequencing methods as a service.
Our R&D team is actively testing new single-cell multi-omic technologies and spatial
modalities to offer additional insight into our clients' biological questions.
single-cell sequencing selection tool
Which single-cell sequencing technology is suitable for my project?
Use our selection tool to receive instant advice on what technology is a good candidate for your project.
Why choose SCD?
We are single-cell sequencing experts
We are 100% focused on single-cell and spatial transcriptomics, enabling us to take on both large-scale projects and create customized solutions for each client project.
Our experience is unmatched in the field
We have been working in the single-cell field since 2012. Our co-founder and CEO Mauro Muraro published our SORT- seq technology, and our R&D consultant is the mind behind VASA-seq. We have experience in over 40 organisms and 30 tissues and are able to quickly adapt workflows for novel samples.
We help you stay ahead of the curve
We are committed to continuously integrating leading-edge technologies into our service offerings to ensure clients have access to the latest advancements. Our R&D department works to both internalize the best commercial platforms and advance our own single-cell innovations.
We work with you as a collaborative partner
We are dedicated to maintaining a high- touch, collaborative relationship with clients as we scale our capacity to accommodate larger projects. We act as a thought partner and a catalyst for biological discovery.
Pioneering 10x Flex on OCT-Embedded Patient Brain Tissue
10x Genomics opened the gates for single-cell sequencing on non-fresh, non-thawed tissue with their Chromium Single Cell Gene Expression Flex (10x Flex) kit. Now, we have been successful in performing…
Immune Profiling of atherosclerosis reveals new therapeutic potential
A team of scientists uses 10x Genomics Single Cell Immune Profiling to characterize T cells in the atherosclerotic plaque. Their results redefine atherosclerosis as an autoimmune disease.
Mechanism of disease: a new hypothesis for atherosclerosis
To elucidate atherosclerosis’ mechanism of disease, Sheffield University researchers analyzed the transcriptomes of single endothelial cells.
Tubuloid differentiation to model the human distal nephron and collecting duct in health and disease
Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer
Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover
The Ultimate Guide to single-cell RNA sequencing
Our ultimate guide is a crash course in single-cell RNA sequencing. Download the ultimate guide to discover: how single-cell sequencing was developed, the basic principles of single-cell RNA sequencing works, how to design your project, and much more.