Research areas Enabling breakthrough research
Single-cell RNA sequencing has revolutionized research in several biological research areas, including oncology, immunology, developmental biology, and neuroscience. Analyzing the gene expression profiles of single cells can provide invaluable insight into the cellular diversity, function, and interactions that drive complex biological processes with the ultimate aim of developing better therapeutics.
Research areas
Oncology
Revolutionize cancer research and discover new treatments by measuring the heterogeneity of the tumor microenvironment and probing the molecular mechanisms underlying cancer development and disease progression.
Immunology
Unlock new insights into the mechanisms underlying immune system function, response to stimuli, and involvement in immuno-oncology treatments.
Developmental Biology
Unravel developmental processes to discover molecular mechanisms behind development, genetic diseases, and regeneration.
Working in another research area?
Single-cell sequencing can be applied in many other research areas: think cardiology, marine biology, toxicology, plant biology, etc. Please contact us if you work in an area that's not listed above. We have experience with a lot of out-of-the-box projects, and we like a challenge.
Case studies
Pioneering 10x Flex on OCT-Embedded Patient Brain Tissue
10x Genomics opened the gates for single-cell sequencing on non-fresh, non-thawed tissue with their Chromium Single Cell Gene Expression Flex (10x Flex) kit. Now, we have been successful in performing…
Immune Profiling of atherosclerosis reveals new therapeutic potential
A team of scientists uses 10x Genomics Single Cell Immune Profiling to characterize T cells in the atherosclerotic plaque. Their results redefine atherosclerosis as an autoimmune disease.
Mechanism of disease: a new hypothesis for atherosclerosis
To elucidate atherosclerosis’ mechanism of disease, Sheffield University researchers analyzed the transcriptomes of single endothelial cells.
Recent publications
iScience
Tumor-derived colorectal cancer organoids induce a unique Treg cell population by directing CD4+ T cell differentiation
Nature Cardiovascular Research
Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration
Immunity
Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis
Information Guide
Discover our single-cell sequencing solutions
Download our information guide to access an overview of Single Cell Discoveries, explore our single-cell sequencing services, learn how to get started, and gain more valuable insights.