Research & Development We are
committed to being on the leading edge

R&D is at the heart of Single Cell Discoveries. We pioneered the SORT-seq, VASA-seq, and Discovery-seq methodologies and are driven to keep innovating new ways to study single-cell multi-omics and spatial modalities. Our team is continuously working to implement better protocols that improve the accuracy, resolution, flexibility, and ultimately value of our services.

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Research and Development at Single Cell Discoveries
Overview

An expert team driving
innovation and versatility

We are driven to innovate

Our team has deep experience with the technology and an insatiable curiosity that keeps our services futureproof by optimizing our methods, assimilating new protocols, and upgrading our infrastructure.

We like challenges

Our R&D unit is eager to work on your non-standard project, whether it is a novel application, a tough tissue, or an uncommon species requiring technological tinkering. We say "yes" to challenges others reject.

We keep you ahead of the curve

We are dedicated to offering clients the most advanced technologies in the single-cell and spatial field to give them an edge against the competition and accelerate their therapeutics towards the clinic.

 

We consistently evolve

Our R&D team is always working on adaptations to our current services to improve client experience and elevate data quality. Recently, we have introduced automated nuclei isolation, targeted amplification, and fixed RNA profiling.

THE R&D TEAM

Meet our experts

Click on a profile to read more personal info.

Dylan Mooijman, head of Research and Development at Single Cell Discoveries
HEAD OF R&D

  

Sabine Tanis, senior R&D scientist at Single Cell Discoveries
TEAM LEAD METHOD DEVELOPMENT

Oriol Llora Batlle, PERSIST-seq scientist at Single Cell Discoveries
TEAM LEAD EXTERNAL R&D ALLIANCES

Darina Sikrova, R&D Scientist at Single Cell Discoveries
R&D SCIENTIST

Doreth Fransen, automation scientist at Single Cell Discoveries
AUTOMATION SCIENTIST

Stefani Giacopazzi, support scientist at Single Cell Discoveries
DATABASE ADMINISTRATOR

Amalia Riga, R&D scientist at Single Cell Discoveries
AUTOMATION SCIENTIST

Recent publications

iScience

Tumor-derived colorectal cancer organoids induce a unique Treg cell population by directing CD4+ T cell differentiation

Case studies

Amsterdam UMC

Pioneering 10x Flex on OCT-Embedded Patient Brain Tissue

10x Genomics opened the gates for single-cell sequencing on non-fresh, non-thawed tissue with their Chromium Single Cell Gene Expression Flex (10x Flex) kit. Now, we have been successful in performing…

10x
Neuroscience
Neuroscience
RNA Flex
COLLABORATIONS AND CONSORTIA

Partnerships play a dual role in our operations. In alignment with our vision, we work on projects that help adapt single-cell applications to diagnostic and therapeutic purposes. Meanwhile, we access resources and experience that fuel our own evolution.

Blog posts

A scientist preparing samples to be sequenced

Discovery-seq: Finding more and better drug targets

Traditional high-throughput drug screening often relies on visual markers that are challenging to quantify and limited in scope. In contrast, RNA sequencing-based screening offers transcriptome-wide quantitative insights, enabling the discovery…

Blog
Knowledge
Identifying more and better drug targets

High-throughput screening: accelerating drug discovery

Drug discovery is a complex and lengthy process that begins with identifying specific molecular targets, such as proteins or genes linked to diseases. Researchers then screen vast libraries of compounds…

Blog
Knowledge
How can we help?

Want to supercharge your project with our services?

Connect with our PhD-level scientists to discuss your biological question, timeline, sample types, and other customizations for your project.