Research & Development
committed to being on the leading edge
R&D is at the heart of Single Cell Discoveries. We pioneered the SORT-seq and VASA-seq methodologies and are driven to keep innovating new ways to study single-cell multi-omics and spatial modalities. Our team is continuously working to implement better protocols that improve the accuracy, resolution, flexibility, and ultimately value of our services.
An expert team driving
innovation and versatility
We are driven to innovate
Our team has deep experience with the technology and an insatiable curiosity that keeps our services futureproof by optimizing our methods, assimilating new protocols, and upgrading our infrastructure.
We like challenges
Our R&D unit is eager to work on your non-standard project, whether it is a novel application, a tough tissue, or an uncommon species requiring technological tinkering. We say "yes" to challenges others reject.
We keep you ahead of the curve
We are dedicated to offering clients the most advanced technologies in the single-cell and spatial field to give them an edge against the competition and accelerate their therapeutics towards the clinic.
We consistently evolve
Our R&D team is always working on adaptations to our current services to improve client experience and elevate data quality. Recently, we have introduced automated nuclei isolation, targeted amplification, and fixed RNA profiling.
Tubuloid differentiation to model the human distal nephron and collecting duct in health and disease
Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer
Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover
Pioneering 10x Flex on OCT-Embedded Patient Brain Tissue
10x Genomics opened the gates for single-cell sequencing on non-fresh, non-thawed tissue with their Chromium Single Cell Gene Expression Flex (10x Flex) kit. Now, we have been successful in performing…
Immune Profiling of atherosclerosis reveals new therapeutic potential
A team of scientists uses 10x Genomics Single Cell Immune Profiling to characterize T cells in the atherosclerotic plaque. Their results redefine atherosclerosis as an autoimmune disease.
Mechanism of disease: a new hypothesis for atherosclerosis
To elucidate atherosclerosis’ mechanism of disease, Sheffield University researchers analyzed the transcriptomes of single endothelial cells.
COLLABORATIONS AND CONSORTIA
Partnerships play a dual role in our operations. In alignment with our vision, we work on projects that help adapt single-cell applications to diagnostic and therapeutic purposes. Meanwhile, we access resources and experience that fuel our own evolution.
Is Bioinformatics Consulting For Me?
Rising to the challenges of single-cell data analysis can be illuminating, or it can be tiresome. That totally depends on the context of your project, team, skills, and schedule. How…
Single-Cell Sequencing in Clinical Trials: Phase-II Studies
Today, single-cell RNA sequencing in Phase-II clinical trials serves one main goal. It is used to further develop an understanding of an authorized drug’s mechanism of action, which results are…
Nuclei Isolation for Single Cell: Which Method?
Nuclei isolation — To produce high-quality data with single nucleus RNA sequencing, it’s important first to find the most fitting nuclei isolation protocol. To be more precise, it’s important to…
How can we help?
Want to supercharge your project with our services?
Connect with our PhD-level scientists to discuss your biological question, timeline, sample types, and other customizations for your project.