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Fluent Omics
SCD is a specialist precision biology CRO supporting pharmaceutical, biotechnology, and academic organizations from discovery through validation and clinical development. It combines single-cell sequencing, spatial transcriptomics, multi-omics, data science, molecular assay development, qPCR, dPCR, proteomics, and regulatory-ready bioanalysis in one organization. Customers work directly with the scientists who design, execute, and interpret their studies. Our services
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What our clients say

"SCD performed a single-cell immune and protein profiling analysis using a bespoke panel on a large set of our blood samples, generating a high-quality dataset. They did a fantastic job in performing the wet lab workflow, ensuring minimal batch effects. The team was professional and responsive, actively working with us to optimize the experimental design and kit chemistry to meet our analytical goals. We were impressed by the overall quality."
Duncan McKenzie, Discovery Lead at IMU Biosciences

"The service of Single Cell Discoveries guarantees a smooth process between customer and company. In case of problems or questions, the scientists reacted competently and immediately, so that answers could be found quickly and flexibly."
Prof. Dr. Stella Autenrieth, Research Group Leader at German Cancer Research Center

"Fantastic job made by a really professional and friendly team. I strongly recommend Single Cell Discoveries for sequencing services."
Samuel García Pérez, Principal Investigator at Galicia Sur Health Research Institute

"The team at Single Cell Discoveries provided outstanding support on a highly challenging project. Their scientific expertise, high-quality data, and consistent responsiveness made the collaboration both efficient and productive. We look forward to collaborating with them again in the near future."
Juan Luis Trincado, Senior Bioinformatician, R&D at Almirall

"Every step of the process has been perfect, starting from the initial informative meeting, where I received useful suggestions, to the experimental phase, which was carried out very quickly. Additionally, communication has been prompt and highly effective."
Andrea Ghiroldi, Staff Scientist at Italfarmaco

"I had a great experience working with Single Cell Discoveries. Service was of excellent quality and fast, and I really appreciated your personalized guidance. I would like to highlight how great it was to work with the data team; it was very easy to communicate with them, and they analyzed our challenging data set exactly as we had in mind, always making sure to understand our needs."
Marta Cuenca-Lopera, Assistant Professor at Center for Translational Immunology, UMC Utrecht
QUALITY ASSURANCE & COMPLIANCE
Built for critical research decisions
Molecular profiling from discovery to targeted validation
We combine advanced discovery technologies with precision validation to support drug development from early research through clinical studies.
- Single-cell, spatial & bulk transcriptomics
- Data analysis & bioinformatics support
- qPCR & dPCR
- Affinity-based proteomics
- Assay development & validation
- ISO 17025 accredited, GLP approved and GCLP compliant
Deep scientific expertise
Our scientists bring deep expertise across transcriptomics, PCR, proteomics and data analysis. While other CROs help to run your assays, we help design the right approach, troubleshoot complex projects and turn biological data into meaningful answers.
Technology choices you can trust
We continuously evaluate new platforms through internal R&D and real-world validation. We adopt technologies only when they clearly improve data quality, robustness, or interpretability. When commercial options fall short, we build and validate proprietary assays and workflows.
Discovery connected to validation
Move from discovering biological signals to understanding and validating what matters, all within one scientific organization. Our combined capabilities create greater continuity between early discovery, data analysis, biomarker and target validation, and clinical applications.
How we support your research
Expertise across therapeutic areas
Immuno-oncology & Oncology
Resolve tumor and immune heterogeneity at single-cell and spatial resolution to identify treatment-responsive and resistant cell states, characterize the tumor microenvironment, and uncover clinically relevant biomarkers. Connect these discoveries with TCR profiling, proteomics and targeted molecular assays to validate and track the signals that matter.
Cell & Gene Therapy
Characterize therapeutic cell populations beyond surface markers and understand how cell state, identity, and function change throughout development. Progress drug targets with biodistribution, shedding assays, vector copy number, and transgene expression using sensitive, GLP-compliant qPCR/dPCR assays suitable for preclinical and clinical development.
CNS & Neurological Disorders
Dissect complex neural tissues and models at cellular and spatial resolution to reveal disease-associated neuronal and cell states that are obscured in bulk measurements. Identify molecular signatures and pathways linked to disease or treatment response and carry selected findings into targeted validation.
Toxicology & Safety
Measure transcriptome-wide responses across hundreds to thousands of compounds, concentrations, or conditions to identify dose-responsive signatures and investigate mechanisms of toxicity. Follow promising molecular signals into targeted validation to support more informed compound and safety decisions.
Immunology & Inflammation
Resolve heterogeneous immune populations, activation states, and clonal responses to understand how immune systems change across disease, treatment, and experimental conditions. Combine gene-expression, immune-repertoire, and protein-level measurements to characterize immune responses from discovery through validation.
Biomarker Discovery & Clinical Research
Discover candidate biomarkers using transcriptomics and proteomics, then translate promising signals into targeted assays for larger sample cohorts and clinical studies. Our combined discovery and GLP and GCLP capabilities help bridge the gap between finding a biological signal and measuring it reproducibly in the samples that matter.
Our services
Single-Cell Sequencing
Data Analysis
- In addition to the standard data analysis included with every project, we offer dedicated data consulting to support advanced interpretation and custom analytical needs.
Multiomics
- BioSkryb Genomics' ResolveServices™
- High-throughput FFPE Proteomics with Sapient
- Olink proteomics with TATAA Biocenter
Sequencing Service
- We are the fastest sequencing service in Europe, delivering high-quality data in just 2 weeks with expert support, flexible data formats, and interactive reports.
Custom Assays
- Our R&D team continuously customizes existing methods to fit each unique experimental need.
Recent publications
bioRxiv
A Double-Negative Prostate Cancer Subtype is Vulnerable to SWI/SNF-Targeting Degrader Molecules
bioRxiv
SP140 limits type I interferon-driven pathology, preserving T cell motility and promoting resistance in tuberculosis
Nature Communications
Targeted CRISPR-Cas9 screening identifies core transcription factors controlling murine haemato-endothelial fate commitment
Our Blog Posts
Gene set enrichment analysis: From Genes to Biological Processes
Gene set enrichment analysis (GSEA) helps translate gene-level expression changes into broader biological processes. It starts with a ranked list of all tested genes, usually based on a signed statistic…
How to Prevent Single-Cell Sequencing Delays in Pharmaceutical Research
Single-cell sequencing has become an indispensable tool for pharmaceutical R&D. From identifying disease-driving cell populations to discovering predictive biomarkers and evaluating drug response, it provides a level of biological resolution…
Ultra-Low Input RNA-seq: Strategies for Limited or Degraded Samples
RNA sequencing (RNA-seq) has become one of the most powerful tools for studying gene expression. However, not every project starts with abundant, high-quality RNA. Researchers often work with tiny biopsies,…
How can we help?
Want to supercharge your project with single-cell insights?
Connect with our PhD-level scientists to discuss your biological question, timeline, sample types, and other customizations for your single-cell analysis.