"SCD performed a single-cell immune and protein profiling analysis using a bespoke panel on a large set of our blood samples, generating a high-quality dataset. They did a fantastic job in performing the wet lab workflow, ensuring minimal batch effects. The team was professional and responsive, actively working with us to optimize the experimental design and kit chemistry to meet our analytical goals. We were impressed by the overall quality."
Duncan McKenzie, Discovery Lead at IMU Biosciences
"The service of Single Cell Discoveries guarantees a smooth process between customer and company. In case of problems or questions, the scientists reacted competently and immediately, so that answers could be found quickly and flexibly."
Prof. Dr. Stella Autenrieth, Research Group Leader at German Cancer Research Center
"Fantastic job made by a really professional and friendly team. I strongly recommend Single Cell Discoveries for sequencing services."
Samuel García Pérez, Principal Investigator at Galicia Sur Health Research Institute
"Every step of the process has been perfect, starting from the initial informative meeting, where I received useful suggestions, to the experimental phase, which was carried out very quickly. Additionally, communication has been prompt and highly effective."
Andrea Ghiroldi, Staff Scientist at Italfarmaco
"I had a great experience working with Single Cell Discoveries. Service was of excellent quality and fast, and I really appreciated your personalized guidance. I would like to highlight how great it was to work with the data team; it was very easy to communicate with them, and they analyzed our challenging data set exactly as we had in mind, always making sure to understand our needs."
Marta Cuenca-Lopera, Assistant Professor at Center for Translational Immunology, UMC Utrecht
Unmatched expertise in single-cell
We have worked with single-cell since the early days, across multiple technology generations. Across 50+ organisms and 30+ tissue types, we’ve seen how workflows behave in real biological edge cases. That experience helps us anticipate risks early and deliver decision-ready data.
Technology choices you can trust
We continuously evaluate new platforms through internal R&D and real-world validation. We adopt technologies only when they clearly improve data quality, robustness, or interpretability. When commercial options fall short, we build and validate proprietary assays and workflows.
We are your collaborative partner
We act as a thought partner, not just a service provider. We help shape experimental design, make trade-offs explicit, and align work with downstream objectives. This approach supports complex, multi-phase programs where confidence and consistency matter.
Immuno-oncology
We help immuno-oncology researchers understand tumor and immune heterogeneity by capturing high-resolution transcriptomes that reveal rare, clinically relevant cell states and differential transcriptional programs driving immunosuppression, resistance, and outcome. These insights are often missed by conventional bulk or population-level methods.
CNS Disorders
We deliver deep transcriptomic insight into complex neural tissues by profiling neuronal and glial diversity with exceptional resolution to uncover rare and disease-associated cell states, transcriptional programs, and gene signatures that illuminate mechanisms underlying neurological and neurodevelopmental disorders. Our full-length single-cell and bulk RNA-seq solutions enable isoform splicing analysis at unparalleled sensitivity and resolution.
Target Discovery
We support target discovery by linking differential transcriptional programs and gene signatures to disease-relevant cell states resolved at high resolution. This enables prioritization of molecular targets with substantiated biological context and mechanistic relevance. By combining DRUG-seq, single-cell sequencing, and spatial transcriptomics, we specialize in quickly moving from hit-finding to validation. This helps our clients identify better targets faster.
Cell & Gene Therapy
We advance cell and gene therapy development through high-resolution characterization of therapeutic cell populations, enabling sensitive detection of transcriptional states and gene signatures beyond surface markers. We support lead optimization by mapping compound efficacy across cell types and provide actionable MoA insights by revealing transcriptomic treatment effects at the relevant cell-population level, not just in bulk or organs.
Single-cell spatial transcriptomics pinpoints drug-tolerant niches in colorectal-cancer liver metastasis
In this case study, we describe our collaboration with the Colorectal Cancer Laboratory at IRB Barcelona. Through our end-to-end spatial workflow service built around Visium HD technology, we supported the identification of distinct micro-niches of colorectal cancer cells that persist after FOLFOX chemotherapy. Together, these insights provide a roadmap for developing more effective combination therapies.
The cost of single-cell sequencing and how to keep it under control
Single-cell sequencing has a reputation for being expensive. And yes, if done without planning, it absolutely is. But the real cost problem usually isn’t the technology itself. It’s poor experimental…
Transcriptomics vs Proteomics in the Single-Cell and Spatial Era
Understanding complex tissues and diseases requires more than a single readout. By combining bulk, single-cell, and spatial transcriptomics with targeted proteomic validation, we can now follow and understand biology from…
