Parse Biosciences

Evercode Single Cell Whole Transcriptome

Scalable and instrument free single-cell sequencing. Evercode captures the transcriptomes of up to millions of individual cells in a single experiment, while dramatically reducing batch effects.

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Single-cell applications at Single Cell Discoveries
Features of Evercode Whole Transcriptome

Leveraging our sample preparation expertise for scalable and large multi-million cell projects

Evercode by Parse Biosciences is a single-cell sequencing technology that utilizes combinatorial barcoding, making it a scalable, flexible, and instrument-free solution. By fixing and storing cells before barcoding, we enable unprecedented experimental design freedom, minimize batch effects, and preserve biological states. With industry-leading sensitivity and seamless integration for whole transcriptome, immune profiling, and CRISPR screens, we empower researchers with Evercode by generating deeper, more reliable insights at scale. Evercode Whole Transcriptome enables projects ranging from discovery studies to atlas-scale cell mapping.

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Benefits of Evercode

Massive scale

We can profile from tens of thousands to millions of cells per run.

Multi-site/Longitudinal studies

Fix and store samples before sending them to us in one go, simplifying logistics and enabling multi-site or longitudinal studies.

High-quality data

Detect lowly-expressed genes and reduce ambient RNA.

Compatible with non-model species

The simple workflow of Evercode allows us to sequence a broad range of sample types.

Applications of Evercode

Developmental biology and stem cell research

We can track lineage relationships and capture dynamic transcriptional changes across developmental time points with Evercode’s high-resolution single-cell mapping.

Cancer and immunology studies

We can profile tumor heterogeneity, immune cell interactions, and clonal diversity to uncover the mechanisms underlying disease and therapeutic response.

Large, multi-center projects​

You can leverage sample fixation and batching to harmonize data across sites and time points, minimizing batch effects while scaling to millions of cells.

Drug discovery and pharmacogenomics

We can identify cell-type–specific drug effects, gene expression signatures, and biomarkers that inform precision medicine.

Our services with Evercode:

As a certified service provider, we deliver high-quality single-cell sequencing services using Parse Biosciences’ Evercode technology:

  • Evercode WT (Whole Transcriptome): Comprehensive profiling of gene expression across the entire transcriptome at single-cell resolution.

  • Evercode TCR: Simultaneous capture of T-cell receptor sequences and transcriptomes to connect clonotypes with functional states.

  • Evercode BCR: Profiling of B-cell receptor heavy and light chains together with transcriptomes for immune repertoire analysis.

  • Evercode CRISPR Detect: Combined detection of CRISPR edits and transcriptomes to enable high-throughput functional screens.

FAQ
How are projects priced?

Pricing depends on the number of samples, the area to be covered, sequencing depth, and any required protocol modifications. Your account manager can give pricing information specific to your project’s requirements during consultations.