Accelerate your research
Single Cell
Sequencing
United Kingdom
Single Cell Discoveries, a top provider of single-cell RNA sequencing services in the United Kingdom (UK), is dedicated to assisting researchers and scientists in gaining a comprehensive understanding of single-cell biology. Utilizing advanced technology and a skilled team of scientists, we offer unmatched insights into gene expression profiling and cell typing across various organisms.
Single-Cell Sequencing
Service Provider in the UK
Single-cell RNA sequencing is a cutting-edge technology that has revolutionized the field of biology. By analyzing the transcriptomic material of individual cells, researchers are able to study cellular diversity and gene expression on a level that was previously impossible. This technology has a wide range of applications, including the study of cancer, immune system function, and neurological disorders.
We work closely with our clients
At Single Cell Discoveries, we offer a full range of single-cell sequencing services, including 10x Genomics, SORT-seq, and VASA-seq. Our team of experts will work closely with you to determine the best approach for your specific research needs.
We tailor our services to your need
Our state-of-the-art facility is equipped with the latest technology and robots, allowing us to provide fast, accurate results. We're available to answer any questions you may have along the way. And we are experienced in working with researchers from a wide range of scientific fields, and we are here to provide the support and guidance you need to make the most of your single-cell sequencing data.
Shipping from the United Kingdom
Quickly transfer your samples from the United Kingdom to Single Cell Discoveries via TNT or other couriers. Order the cell-capture plates required for SORT-seq and VASA-seq experiments online and have them sent to your laboratory.
If you are a researcher or scientist in the United Kingdom looking to gain a deeper understanding of individual cells, we invite you to contact Single Cell Discoveries today to learn more about our services. We look forward to helping you achieve your research goals.
Get the Information Guide
Download our information guide to access an overview of Single Cell Discoveries, explore our single-cell sequencing services, learn how to get started, and gain more valuable insights.
Our services
We offer single-cell, spatial and bulk transcriptomics.
Our R&D team is actively developing novel single-cell sequencing technologies,
multi-omic applications and spatial transcriptomics.
Single-cell sequencing
SORT-Seq
Single-cell transcriptomics method utilizing 384-well plates, ideal for low cell counts, FACS sorted populations, and pilot projects. Developed by our founder, exclusively offered by us.
10x Genomics
Certified Service Provider of the 10x Genomics Single Cell Gene Expression and Single Cell Immune Profiling solutions, ideal for high- throughput applications.
VASA-Seq
Single-cell RNA sequencing method for full- length and total RNA, ideal for analyzing non- coding RNA and complete transcriptomes. Developed by one of our team members, exclusively offered by us.
Spatial transciptomics
Spatial Transriptomics
Transcriptomics method for analysis of spatial gene expression and histology, ideal for the study of cell localization and cell-cell interactions.
Pooled cells
Bulk RNA Sequencing
Comprehensive transcriptome analysis of pooled cell populations, ideal for limited starting material and large projects requiring cell population data.
“It’s the expertise that Single Cell Discoveries has in single-cell and T cell receptor sequencing, even though you are flexible, that makes it preferential for us to work with an industry partner like you.”
"Fantastic job made by a really professional and friendly team. I strongly recommend Single Cell Discoveries for sequencing services."
“What we appreciate most is the nature of the collaboration. With Single Cell Discoveries, we could discuss the design of our 10x Genomics experiments, which analyses to do, and how to solve our challenges.”
The premier single-cell CRO
Accelerate your research with our tailored single-cell sequencing solutions
Located in Utrecht, the Netherlands, our purpose-built single-cell sequencing lab is operated by a team of PhD-level scientists, some of whom have pioneered the single-cell platforms we employ to deliver exceptional service. At Single Cell Discoveries, we are dedicated to crafting customized solutions for your unique challenges, ensuring rapid turnaround times, and unlocking high-impact biological insights. We eat, sleep, and breathe single-cell biology so you can focus on advancing your discovery program.
Trusted by
How we supercharge
your research
Project Design
- Strategize with our PhD-level account executives to decide between multiple single-cell technologies, including two exclusively offered by us.
- Leverage our experience with 200+ clients over 1000+ unique projects.
Sample Processing
- Run in our purpose-built single-cell lab with Illumina Novaseq X.
- Benefit from our experience with 8500+ samples sequenced in 40+ organisms and 30+ tissue types with over 10M single cells sequenced.
Data Analysis
- Gain quick insights into your single-cell data with our preliminary analysis report with QC, clustering, and differential gene expression.
- Uncover biological insights through custom data analysis with our bioinformaticians who have processed over 50 terabytes of single-cell data.
Step 1
Consultation
Every project starts with one or more free consultations because no two single-cell projects are the same. Our experienced PhD-level team discusses your biological question, sample type, planning, data analysis options, and other wishes. This will ensure you select the best method for your project and can hit the ground running.
Step 2
Sample Preparation
For 10x Genomics, create a single-cell suspension from your sample and either cryopreserve or methanol-fix the cells. For SORT-seq, FACS-sort the single cells into the wells of our cell capture plates. Then, send your samples to our lab on dry ice. In the case of nuclei, the sample preparation depends on the project.
Step 3
Processing in Our Lab
Our experienced team performs the 10x Genomics protocol in our lab. We sequence the libraries on our Illumina NovaSeq X Plus or NextSeq 2000. We'll do multiple QC checks and keep you informed of the status of your project.
Step 4
Data Analysis
Our data team performs preliminary data analysis using a Seurat pipeline, checks the data quality and discusses irregularities with our lab team if necessary. You will receive the raw data files, data report, and guiding explanations. Talk to our data consulting team for help or request additional assessments such as pseudotime and gene set enrichment analysis.
FAQ
That depends on your biological question, sample type, and budget. Feel free to schedule a meeting with one of our experts to discuss your project in more detail. We'll make sure to advise you on the best platform for your project.
While this is possible in principle, it will likely require some batch effect correction. Different technologies will yield slightly different results due to technology-specific technical quirks and other biases. However, with batch effect correction and a clear biological difference between the different populations in your samples, it should be possible to mix with data from other platforms.
Pricing depends on the cells per sample, sequencing depth, viability of input materials, and required protocol modifications. Your account manager can give pricing information specific to your project's requirements during consultations.
Information Guide
Discover our single-cell sequencing solutions
Download our information guide to access an overview of Single Cell Discoveries, explore our single-cell sequencing services, learn how to get started, and gain more valuable insights.