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Explore our featured blogs for the latest insights in single-cell sequencing. Stay informed, unravel complex concepts, and discover exciting applications in this cutting-edge field.

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Microscopic image of isolated nuclei for single cell RNA sequencing with labeled high-quality nuclei, low-quality nuclei, and debris.

Nuclei Isolation for Single Cell: Which Method?

Nuclei isolation — To produce high-quality data with single nucleus RNA sequencing, it’s important first to find the most fitting nuclei isolation protocol. To be more precise, it’s important to…

Lymphoid cells and TB infection

10x Genomics Multiome vs. scRNA-seq and scATAC-seq

10x Genomics Multiome – 10x Genomics’ combinatory technology Multiome Single Cell Gene Expression + ATAC can be a perfect tool for many intricate questions in drug development. In two blog posts,…

AAV gene therapy optimization with single-cell sequencing

AAV gene therapy optimization with single-cell sequencing

This blog evaluates the demand for AAV gene therapy optimization and Single Cell Discoveries’ response: single-cell biodistribution and transgene expression assay for AAV drug developers. In the rapidly evolving landscape…

scATAC-seq technology chromatin accessibility Single Cell ATAC explained

How scATAC-seq works

In this blog, we describe how single-cell ATAC-seq (scATAC-seq) works, what its results tell you, and how you can combine scATAC-seq with single-cell RNA sequencing. In the rapidly evolving landscape…

Posterized spatial single-cells in a 2D epithelial patch colored in bands of 1000 microns. Credit: Smit et al. (2022)

Spatially annotated SORT-seq

What happens if you combine SORT-seq and microscopy-based spatial annotation? A group of scientists made that high-tech merger happen, generating a single-cell dataset with high transcript counts and tissue-context information….