Nuclei Isolation for Single Cell: Which Method?
Nuclei isolation — To produce high-quality data with single nucleus RNA sequencing, it’s important first to find the most fitting nuclei isolation protocol. To be more precise, it’s important to…
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Nuclei isolation — To produce high-quality data with single nucleus RNA sequencing, it’s important first to find the most fitting nuclei isolation protocol. To be more precise, it’s important to…
10x Genomics Multiome – 10x Genomics’ combinatory technology Multiome Single Cell Gene Expression + ATAC can be a perfect tool for many intricate questions in drug development. In two blog posts,…
ATAC-seq for single cells — Like any biomedical technique, single-cell ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing: scATAC-seq) has benefits and limitations. Some biological questions it is perfectly fit to…
Single nucleus RNA sequencing is an alternative version of single-cell RNA sequencing with the 10x Genomics Single Cell Gene Expression solution. As the name suggests, sequencing is preceded by a…
This blog evaluates the demand for AAV gene therapy optimization and Single Cell Discoveries’ response: single-cell biodistribution and transgene expression assay for AAV drug developers. In the rapidly evolving landscape…
In this blog, we describe how single-cell ATAC-seq (scATAC-seq) works, what its results tell you, and how you can combine scATAC-seq with single-cell RNA sequencing. In the rapidly evolving landscape…
The 10x Genomics Single Cell Gene Expression Flex (10x Flex) kit for fixed RNA profiling expands sample access to include fresh, formaldehyde-fixed, and FFPE tissues for single-cell or single-nucleus RNA…
What happens if you combine SORT-seq and microscopy-based spatial annotation? A group of scientists made that high-tech merger happen, generating a single-cell dataset with high transcript counts and tissue-context information….