Explore our featured blogs for the latest insights in single-cell sequencing. Stay informed, unravel complex concepts, and discover exciting applications in this cutting-edge field.

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Microscopic image of isolated nuclei for single cell RNA sequencing with labeled high-quality nuclei, low-quality nuclei, and debris.

Nuclei Isolation for Single Cell: Which Method?

Nuclei isolation — To produce high-quality data with single nucleus RNA sequencing, it’s important first to find the most fitting nuclei isolation protocol. To be more precise, it’s important to…

10x Genomics Multiome vs. scRNA-seq and scATAC-seq

10x Genomics Multiome – 10x Genomics’ combinatory technology Multiome Single Cell Gene Expression + ATAC can be a perfect tool for many intricate questions in drug development. In two blog posts,…

ATAC-seq for single cells at Single Cell Discoveries

ATAC-seq for Single Cells: Benefits and Limitations

ATAC-seq for single cells — Like any biomedical technique, single-cell ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing: scATAC-seq) has benefits and limitations. Some biological questions it is perfectly fit to…

AAV gene therapy optimization with single-cell sequencing

AAV gene therapy optimization with single-cell sequencing

This blog evaluates the demand for AAV gene therapy optimization and Single Cell Discoveries’ response: single-cell biodistribution and transgene expression assay for AAV drug developers. In the rapidly evolving landscape…

scATAC-seq technology chromatin accessibility Single Cell ATAC explained

How scATAC-seq works

In this blog, we describe how single-cell ATAC-seq (scATAC-seq) works, what its results tell you, and how you can combine scATAC-seq with single-cell RNA sequencing. In the rapidly evolving landscape…

Posterized spatial single-cells in a 2D epithelial patch colored in bands of 1000 microns. Credit: Smit et al. (2022)

Spatially annotated SORT-seq

What happens if you combine SORT-seq and microscopy-based spatial annotation? A group of scientists made that high-tech merger happen, generating a single-cell dataset with high transcript counts and tissue-context information….