Read about our latest news, updates, top-notch science, and learn more about the ins and outs of single-cell sequencing.
Single-cell CRISPR (scCRISPR) screens have quickly become a game-changer in genomics. scCRISPR screening enables researchers to delve deeply into the functional consequences of gene perturbations at the single-cell level. While…
Rising to the challenges of single-cell data analysis can be illuminating, or it can be tiresome. That depends on the context of your project, team, skills, and schedule. How do…
Today, single-cell RNA sequencing in Phase-II clinical trials serves one main goal. It is used to further develop an understanding of an authorized drug’s mechanism of action, which results are…
Nuclei isolation — To produce high-quality data with single nucleus RNA sequencing, it’s important first to find the most fitting nuclei isolation protocol. To be more precise, it’s important to…
Single Cell in Phase-I Clinical Trials — In this blog post, we take a look at the first documented Phase-I clinical trials that use single-cell RNA sequencing. What have the…
10x Genomics Multiome – 10x Genomics’ combinatory technology Multiome Single Cell Gene Expression + ATAC can be a perfect tool for many intricate questions in drug development. In two blog posts,…
10x Multiome – Almost all medical diseases in need of new therapeutics—including cancer, immune diseases, and neurodegenerative disorders—result from a complex interplay between gene expression and epigenetic programs. In order…
ATAC-seq for single cells — Like any biomedical technique, single-cell ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing: scATAC-seq) has benefits and limitations. Some biological questions it is perfectly fit to…
Single nucleus RNA sequencing is an alternative version of single-cell RNA sequencing with the 10x Genomics Single Cell Gene Expression solution. As the name suggests, sequencing is preceded by a…
Gamma-delta T cells are gaining considerable attention as a powerful immunotherapy tool against cancer. What underpins their promise? How will they be applied in the clinic? Gamma-delta (γδ) T cells…
We’re delighted to announce that we have improved our VASA-seq 1.1 protocol. Vast transcriptome Analysis of Single cells by A-tailing (VASA-seq) is a single-cell sequencing platform for full-length, total RNA…
This blog evaluates the demand for AAV gene therapy optimization and Single Cell Discoveries’ response: single-cell biodistribution and transgene expression assay for AAV drug developers. In the rapidly evolving landscape…